Description

6-Bromo-5-Methoxypicolinonitrile is a versatile and high-value brominated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both bromine and nitrile functional groups, makes it an indispensable intermediate for constructing complex molecules with precision. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of potential drug candidates, particularly in kinase inhibitor and other small-molecule therapeutic research.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated heterocyclic core.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science: Employed in the synthesis of organic electronic materials, such as charge-transport layers or light-emitting components.
• Chemical Biology Probes: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring functionalized picolinonitrile scaffolds.

Basic Information

Product Name	6-Bromo-5-Methoxypicolinonitrile
CAS No.	1112851-37-2
Molecular Formula	C7H5BrN2O
Molecular Weight	213.03 g/mol
Synonyms	5-Methoxy-6-bromopicolinonitrile; 6-Bromo-5-methoxy-2-cyanopyridine; 2-Cyano-6-bromo-5-methoxypyridine; 6-Bromo-5-methoxypyridine-2-carbonitrile; 1112851-37-2; 5-Methoxy-6-bromopyridine-2-carbonitrile
EINECS	Contact for details

Quality Control

Our 6-Bromo-5-Methoxypicolinonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥97.0% (Standard Grade)
Purity (HPLC Area %)	≥98.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Single Unknown Impurity	≤0.5%
Total Impurities	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.