Description

2-[2-(Methylthio)Pyrimidin-4-Yl]-1-[1-(Phenylsulfonyl)-1H-Pyrrolo[2,3-B]Pyridin-5-Yl]Ethanone is a sophisticated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for the development of novel pharmaceutical agents, particularly in kinase inhibitor research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and agrochemical industries for creating new active molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of targeted small-molecule therapeutics, especially kinase inhibitors for oncology and inflammatory diseases.
• Biochemical Research: Used as a reference standard or a probe compound in enzymatic assays and structure-activity relationship (SAR) studies.
• Agrochemical Development: Employed in the research and synthesis of novel crop protection agents with specific modes of action.
• Chemical Biology: Utilized in the design and construction of molecular tools for studying biological pathways and protein functions.
• Process Chemistry: Acts as a starting material or intermediate in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).
• Custom Synthesis: A valuable substrate for contract research organizations (CROs) and CDMOs offering bespoke chemical synthesis services.

Basic Information

Product Name	2-[2-(Methylthio)Pyrimidin-4-Yl]-1-[1-(Phenylsulfonyl)-1H-Pyrrolo[2,3-B]Pyridin-5-Yl]Ethanone
CAS No.	1111638-52-8
Molecular Formula	C22H18N4O3S2
Molecular Weight	450.53 g/mol
Synonyms	1-[1-(Benzenesulfonyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-2-[2-(methylsulfanyl)pyrimidin-4-yl]ethanone; 2-(2-(Methylthio)pyrimidin-4-yl)-1-(1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-5-yl)ethan-1-one; 1-(1-(Phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-5-yl)-2-(2-(methylthio)pyrimidin-4-yl)ethanone; CAS 1111638-52-8
EINECS	Contact for details

Quality Control

Our 2-[2-(Methylthio)Pyrimidin-4-Yl]-1-[1-(Phenylsulfonyl)-1H-Pyrrolo[2,3-B]Pyridin-5-Yl]Ethanone is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and structural identity. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability and batch-to-batch consistency, meeting the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.