Description

5-Bromo-2-Methyl-1-(Phenylsulfonyl)-1H-Pyrrolo[2,3-B]Pyridine is a high-value, multi-functional heterocyclic building block designed for advanced organic synthesis. This compound is critical for medicinal chemistry research and development, serving as a key intermediate in the creation of novel pharmaceutical candidates. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce complex molecular architectures into their target molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of kinase inhibitors and other small molecule drug candidates targeting various therapeutic areas.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) due to its versatile functional groups.
• Agrochemical Development: Serves as a precursor in the research and synthesis of novel active ingredients for crop protection products.
• Chemical Biology Probes: Employed in the development of molecular probes for studying biological pathways and target engagement.
• Material Science Research: Potential intermediate for creating specialized organic electronic materials or ligands for catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP or research-grade conditions.

Basic Information

Product Name	5-Bromo-2-Methyl-1-(Phenylsulfonyl)-1H-Pyrrolo[2,3-B]Pyridine
CAS No.	1111638-01-7
Molecular Formula	C15H11BrN2O2S
Molecular Weight	363.23 g/mol
Synonyms	1H-Pyrrolo[2,3-b]pyridine, 5-bromo-2-methyl-1-(phenylsulfonyl)-; 5-Bromo-2-methyl-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine; 5-Bromo-2-methyl-1-(benzenesulfonyl)-1H-pyrrolo[2,3-b]pyridine; 1-(Phenylsulfonyl)-5-bromo-2-methyl-1H-pyrrolo[2,3-b]pyridine; 5-Bromo-2-methyl-1-tosyl-1H-pyrrolo[2,3-b]pyridine (common name variant); 1111638-01-7 (CAS); Bromo-methyl-phenylsulfonyl-pyrrolopyridine
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Methyl-1-(Phenylsulfonyl)-1H-Pyrrolo[2,3-B]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure high consistency and reliability for your critical research and development work. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.