Description

1H-Pyrrolo[2,3-B]Pyridine, 2,3-Dimethyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)- is a high-purity boronic ester derivative, a critical building block in modern synthetic organic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex carbon-carbon bonds. This advanced intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel heterocyclic compounds and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex drug candidates, especially those containing the privileged pyrrolopyridine scaffold.
• Suzuki-Miyaura Cross-Coupling: Enables the efficient and selective formation of biaryl and heterobiaryl bonds in medicinal chemistry and materials science research.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides that require specific heterocyclic architectures.
• Material Science Research: Serves as a precursor for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Biology & Probe Development: Utilized in creating molecular probes and tool compounds for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects requiring functionalized pyrrolopyridine cores.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine, 2,3-Dimethyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-
CAS No.	1111637-99-0
Molecular Formula	C15H23BN2O2
Molecular Weight	274.17 g/mol
Synonyms	2,3-Dimethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridine; 2,3-Dimethyl-1H-pyrrolo[2,3-b]pyridin-5-ylboronic acid pinacol ester; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dimethyl-1H-pyrrolo[2,3-b]pyridine; 2,3-Dimethyl-5-(pinacolboryl)-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine-5-boronic acid, 2,3-dimethyl-, pinacol ester; 2,3-Dimethyl-1H-pyrrolo[2,3-b]pyridine-5-boronic acid pinacol ester; Boronic acid, B-[2,3-dimethyl-1H-pyrrolo[2,3-b]pyridin-5-yl]-, pinacol ester
EINECS	Contact for details

Quality Control

Our production of 1H-Pyrrolo[2,3-B]Pyridine, 2,3-Dimethyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. All products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) when opening the container for use to prevent degradation. For long-term storage, consider storing under an inert gas blanket.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.