Description

3-Pyridinemethanol, 5-Bromo-2-Fluoro-α-Methyl- is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its unique halogenated pyridine structure makes it a critical intermediate for constructing complex molecules with tailored biological and physical properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Useful for designing molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	3-Pyridinemethanol, 5-Bromo-2-Fluoro-α-Methyl-
CAS No.	1111637-73-0
Molecular Formula	C7H7BrFNO
Molecular Weight	220.04 g/mol
Synonyms	5-Bromo-2-fluoro-α-methyl-3-pyridinemethanol; (5-Bromo-2-fluoropyridin-3-yl)ethanol; 1-(5-Bromo-2-fluoropyridin-3-yl)ethanol; 5-Bromo-2-fluoro-3-(1-hydroxyethyl)pyridine; α-Methyl-5-bromo-2-fluoro-3-pyridinemethanol
EINECS	Contact for details

Quality Control

Our production of 3-Pyridinemethanol, 5-Bromo-2-Fluoro-α-Methyl- adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment, supporting cGMP and ISO 9001 compliant workflows for our global partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.