Description

6-Acetamido-4-Methylpyridine-3-Boronic Acid is a high-purity, functionalized pyridine boronic acid derivative, serving as a critical building block in modern synthetic chemistry. Its value lies in its dual functionality, where the boronic acid group enables efficient Suzuki-Miyaura cross-coupling reactions, and the acetamido substituent provides a versatile handle for further derivatization. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for constructing complex heterocyclic scaffolds in drug discovery and advanced material synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in creating novel fungicides and herbicides with enhanced efficacy and selectivity.
• Material Science: Employed in the development of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Biology & Proteomics: Acts as a versatile linker or probe in bioconjugation and the development of chemical tools for biological target engagement.
• Catalyst & Ligand Development: Serves as a starting material for synthesizing novel N,O-bidentate ligands used in transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: A valuable substrate for custom synthesis services catering to R&D and pilot-scale production needs.

Basic Information

Product Name	6-Acetamido-4-Methylpyridine-3-Boronic Acid
CAS No.	1111637-72-9
Molecular Formula	C9H13BN2O3
Molecular Weight	208.03 g/mol
Synonyms	4-Methyl-6-acetamidopyridine-3-boronic acid; 3-Borono-6-acetamido-4-methylpyridine; (6-Acetamido-4-methylpyridin-3-yl)boronic acid; 6-Acetylamino-4-methylpyridine-3-boronic acid; 4-Methyl-6-acetylaminopyridine-3-boronic acid; 1111637-72-9; 6-Acetamido-4-methyl-3-pyridineboronic acid
EINECS	Contact for details

Quality Control

Our 6-Acetamido-4-Methylpyridine-3-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.