Description

1H-Pyrrolo[2,3-B]Pyridine-1-Carboxylic Acid, 5-Bromo-2,3-Dihydro-3-Methyl-, 1,1-Dimethylethyl Ester is a high-purity, advanced pharmaceutical intermediate crucial for modern drug discovery and development. This compound serves as a key synthetic building block for constructing complex heterocyclic molecules with significant biological activity. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the synthesis of novel therapeutic agents, particularly in oncology and central nervous system (CNS) research.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of active pharmaceutical ingredients (APIs) and drug candidates.
• Oncology Research: Used in the development of kinase inhibitors and other targeted cancer therapies due to its privileged pyrrolopyridine scaffold.
• CNS Drug Discovery: Serves as a core structure for synthesizing compounds targeting neurological disorders.
• Agrochemical Synthesis: Employed in the research and development of novel pesticides and herbicides.
• Material Science Research: Investigated as a precursor for organic electronic materials and ligands in catalysis.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations for custom synthesis and process development projects.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine-1-Carboxylic Acid, 5-Bromo-2,3-Dihydro-3-Methyl-, 1,1-Dimethylethyl Ester
CAS No.	1111637-66-1
Molecular Formula	C14H17BrN2O2
Molecular Weight	325.20 g/mol
Synonyms	tert-Butyl 5-bromo-3-methyl-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine-1-carboxylate; 5-Bromo-3-methyl-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine-1-carboxylic acid tert-butyl ester; 1-Boc-5-bromo-3-methyl-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine; 5-Bromo-3-methyl-1,2,3,4-tetrahydropyrrolo[2,3-b]pyridine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine-1-Carboxylic Acid, 5-Bromo-2,3-Dihydro-3-Methyl-, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements for research or cGMP-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.