Description

5-(4-Fluoro-3-(Trifluoromethyl)Phenyl)Pyridin-2-Amine is a high-purity, advanced pharmaceutical intermediate characterized by its unique fluorinated aromatic structure. This compound is of significant commercial importance for its role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular interactions. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential kinase inhibitors and other small-molecule drug candidates.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging the stability imparted by the trifluoromethyl group.
• Material Science: Serves as a precursor for functionalized ligands and monomers used in advanced polymeric materials.
• Organic Synthesis: Employed in cross-coupling reactions and as a versatile amine-containing scaffold for further chemical derivatization in medicinal chemistry.

Basic Information

Product Name	5-(4-Fluoro-3-(Trifluoromethyl)Phenyl)Pyridin-2-Amine
CAS No.	1110656-35-3
Molecular Formula	C12H8F4N2
Molecular Weight	256.20 g/mol
Synonyms	2-Amino-5-[4-fluoro-3-(trifluoromethyl)phenyl]pyridine; 5-(4-Fluoro-3-trifluoromethylphenyl)-2-pyridinamine; 5-(4-Fluoro-3-(trifluoromethyl)phenyl)pyridin-2-amine; 1110656-35-3; 5-(4-Fluoro-3-(trifluoromethyl)phenyl)-2-aminopyridine
EINECS	Contact for details

Quality Control

Our production of 5-(4-Fluoro-3-(Trifluoromethyl)Phenyl)Pyridin-2-Amine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All material is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, generated using validated analytical methods such as HPLC, GC, and NMR. We support compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.