Description

4-Bromo-1,2-Bis[[(1,1-Dimethylethyl)Dimethylsilyl]Oxy]Benzene is a high-purity, organosilicon-protected catechol derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in providing a protected, reactive aromatic scaffold that enables precise functionalization for complex molecule construction. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality building blocks for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex active pharmaceutical ingredients (APIs), particularly those containing substituted benzene or catechol motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Polymer and Material Science: Intermediate for synthesizing monomers and functional additives for high-performance polymers and advanced materials.
• Organic Electronics: Potential precursor in the development of organic semiconductors and charge-transport materials.
• Chemical Research: A versatile reagent for academic and industrial R&D in methodologies involving bromoarenes and silyl-protected phenols.

Basic Information

Product Name	4-Bromo-1,2-Bis[[(1,1-Dimethylethyl)Dimethylsilyl]Oxy]Benzene
CAS No.	1108192-19-3
Molecular Formula	C20H37BrO2Si2
Molecular Weight	445.59 g/mol
Synonyms	4-Bromo-1,2-bis(tert-butyldimethylsilyloxy)benzene; 1,2-Bis[(tert-butyldimethylsilyl)oxy]-4-bromobenzene; 4-Bromocatechol bis(TBDMS) ether; 4-Bromo-1,2-di-O-tert-butyldimethylsilylbenzene; 4-Bromobenzene-1,2-diyl bis(tert-butyldimethylsilyl) ether; TBDMS-protected 4-bromocatechol; 4-Br-1,2-(OTBDMS)2-Benzene
EINECS	Contact for details

Quality Control

Our 4-Bromo-1,2-Bis[[(1,1-Dimethylethyl)Dimethylsilyl]Oxy]Benzene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to verify identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.