Description

3-(5-Chloropyridin-2-Yl)-3-Oxopropanenitrile is a high-value, versatile chemical intermediate featuring a chloropyridine core linked to a cyanoacetone moiety. This compound matters for its role as a critical building block in the synthesis of complex heterocyclic molecules, enabling the development of advanced materials and active ingredients. It is primarily needed by research chemists and process development teams in the pharmaceutical and agrochemical industries for creating novel compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Serves as a building block for developing new generation herbicides, insecticides, and fungicides with improved efficacy and selectivity.
• Material Science Research: Used in the development of organic semiconductors, ligands for catalysis, and other functional organic materials.
• Chemical Research & Development: A versatile synthon for constructing complex pyridine-based heterocycles in academic and industrial R&D settings.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific molecule production.

Basic Information

Product Name	3-(5-Chloropyridin-2-Yl)-3-Oxopropanenitrile
CAS No.	1107053-87-1
Molecular Formula	C8H5ClN2O
Molecular Weight	180.59 g/mol
Synonyms	3-(5-Chloro-2-pyridinyl)-3-oxopropanenitrile; 3-Oxo-3-(5-chloropyridin-2-yl)propanenitrile; 5-Chloro-2-pyridyl cyanomethyl ketone; 2-Acetyl-5-chloropyridine carbonitrile; (5-Chloro-2-pyridinyl)oxoacetonitrile; 3-(5-Chloro-2-pyridyl)-3-oxopropionitrile; 1107053-87-1
EINECS	Contact for details

Quality Control

Our 3-(5-Chloropyridin-2-Yl)-3-Oxopropanenitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.