Description

5-Bromo-2-(2,4-difluoro-phenoxy)-pyridine is a high-purity, advanced pharmaceutical intermediate characterized by its halogenated pyridine-phenoxy ether structure. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) targeting complex disease pathways. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate its unique halogenated scaffold into new molecular entities.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially in kinase inhibitor and antiviral research.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging its difluorophenoxy moiety.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the creation of specialty polymers and liquid crystals.
• Chemical Biology Probe Development: Employed to create tool compounds for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific target molecules on a commercial scale.

Basic Information

Product Name	5-Bromo-2-(2,4-difluoro-phenoxy)-pyridine
CAS No.	1105663-74-8
Molecular Formula	C11H6BrF2NO
Molecular Weight	286.07 g/mol
Synonyms	5-Bromo-2-(2,4-difluorophenoxy)pyridine; 2-(2,4-Difluorophenoxy)-5-bromopyridine; 5-Bromo-2-(2,4-difluorophenoxy)pyridine; Pyridine, 5-bromo-2-(2,4-difluorophenoxy)-; 1105663-74-8
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-2-(2,4-difluoro-phenoxy)-pyridine is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including HPLC, NMR, and GC-MS analysis, to ensure compliance with industry standards and customer-specific requirements. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. This material is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.