Description

1-Azetidinecarboxylic Acid, 3-(2-Methoxy-2-Oxoethylidene)-, 1,1-Dimethylethyl Ester is a high-value, protected azetidine derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in providing a reactive, functionalized azetidine scaffold, enabling the efficient construction of complex nitrogen-containing heterocycles. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and exploring new chemical space.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel azetidine-based drug candidates, including protease inhibitors and other bioactive molecules.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that incorporate the azetidine ring for enhanced biological activity.
• Chemical Synthesis: Serves as a versatile precursor for ring-expansion reactions, cycloadditions, and the introduction of functionalized heterocycles into more complex structures.
• Material Science: Potential monomer or intermediate for creating specialized polymers with unique thermal or mechanical properties derived from the azetidine moiety.
• Academic & R&D: A valuable reagent for methodological studies in organic synthesis and medicinal chemistry research programs.

Basic Information

Product Name	1-Azetidinecarboxylic Acid, 3-(2-Methoxy-2-Oxoethylidene)-, 1,1-Dimethylethyl Ester
CAS No.	1105662-87-0
Molecular Formula	C11H17NO4
Molecular Weight	227.26 g/mol
Synonyms	tert-Butyl 3-(2-methoxy-2-oxoethylidene)azetidine-1-carboxylate; 1-Boc-3-(2-methoxy-2-oxoethylidene)azetidine; 3-(2-Methoxy-2-oxoethylidene)azetidine-1-carboxylic acid tert-butyl ester; Azetidine-1-carboxylic acid, 3-(2-methoxy-2-oxoethylidene)-, 1,1-dimethylethyl ester; 1-(tert-Butoxycarbonyl)-3-(methoxycarbonylmethylene)azetidine
EINECS	Contact for details

Quality Control

Our production of 1-Azetidinecarboxylic Acid, 3-(2-Methoxy-2-Oxoethylidene)-, 1,1-Dimethylethyl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and GC-MS. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its sensitivity, the container should be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent oxidation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.