Description

(2,6-Difluoro-3-Pyridyl)Methanol CAS NO 1105510-11-9 is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in its unique difluoropyridine scaffold, which is prized for modulating the physicochemical and metabolic properties of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients with enhanced efficacy and stability.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and central nervous system (CNS) targeted drugs.
• Agrochemical Synthesis: Building block for novel herbicides, fungicides, and insecticides, leveraging fluorine's ability to improve lipophilicity and biological activity.
• Ligand & Catalyst Development: Used in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions in fine chemical manufacturing.
• Material Science Research: Precursor for functionalized polymers and advanced organic electronic materials due to its aromatic fluorine substituents.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects.
• Life Science Research: Utilized in academic and industrial R&D for probing biochemical pathways and developing diagnostic tools.

Basic Information

Product Name	(2,6-Difluoro-3-Pyridyl)Methanol
CAS No.	1105510-11-9
Molecular Formula	C6H5F2NO
Molecular Weight	145.11 g/mol
Synonyms	2,6-Difluoropyridin-3-ylmethanol; 3-Pyridinemethanol, 2,6-difluoro-; (2,6-Difluoropyridin-3-yl)methanol; 2,6-Difluoro-3-hydroxymethylpyridine; 2,6-Difluoro-3-pyridylcarbinol; 3-(Hydroxymethyl)-2,6-difluoropyridine
EINECS	Contact for details

Quality Control

Our (2,6-Difluoro-3-Pyridyl)Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP standards where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.