Description

2-Chloro-3-[(2-Fluorobenzyl)Oxy]Pyridine is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its molecular architecture, featuring a halogenated pyridine core and a fluorinated benzyloxy side chain, makes it a critical intermediate for constructing complex pharmacophores. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors. It enables the efficient synthesis of novel compounds targeting a range of biological activities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates in central nervous system (CNS) and oncology research.
• Agrochemical Development: Used in the research and production of advanced pesticides and herbicides, where its structural motifs can contribute to novel modes of action.
• Ligand Synthesis: Serves as a building block for creating specialized ligands used in catalysis and material science applications.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences industry.
• Academic & Industrial R&D: Utilized in research laboratories for methodological development and exploring new chemical spaces in medicinal chemistry.

Basic Information

Product Name	2-Chloro-3-[(2-Fluorobenzyl)Oxy]Pyridine
CAS No.	1105190-67-7
Molecular Formula	C12H9ClFNO
Molecular Weight	237.66 g/mol
Synonyms	2-Chloro-3-((2-fluorobenzyl)oxy)pyridine; 3-((2-Fluorobenzyl)oxy)-2-chloropyridine; 2-Chloro-3-(2-fluorobenzyloxy)pyridine; Pyridine, 2-chloro-3-[(2-fluorophenyl)methoxy]-; 1105190-67-7; 2-Chloro-3-(o-fluorobenzyloxy)pyridine
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-[(2-Fluorobenzyl)Oxy]Pyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring full traceability and compliance with your research or production specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP and ISO standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider holding under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.