Description

(4S,Trans)-1,1-Dimethylethyl-6-Aminoethyl-2,2-Dimethyl-1,3-Dioxane-4-Acetate is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. Its value lies in its protected amino and carboxylate functional groups, which are crucial for the controlled construction of complex molecules, particularly in pharmaceutical research. This compound is essential for chemists and R&D teams in the pharmaceutical, agrochemical, and fine chemical industries who require precise intermediates for developing new active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for candidates requiring specific stereochemistry.
• Peptidomimetic Synthesis: Used in the construction of peptide analogs and mimetics due to its protected amino acid-like structure, aiding in drug discovery for metabolic and neurological targets.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing sophisticated chiral ligands used in asymmetric hydrogenation and other catalytic transformations.
• Agrochemical Research: Employed in the development of new, more selective herbicides, fungicides, and insecticides where chirality impacts biological activity.
• Fine Chemical Production: Utilized in custom synthesis and the manufacture of high-value specialty chemicals for electronics and material science applications.
• Academic & Institutional R&D: A valuable reagent for universities and research institutes conducting studies in synthetic methodology and medicinal chemistry.

Basic Information

Product Name	(4S,Trans)-1,1-Dimethylethyl-6-Aminoethyl-2,2-Dimethyl-1,3-Dioxane-4-Acetate
CAS No.	1105067-89-7
Molecular Formula	C15H29NO5
Molecular Weight	303.40 g/mol
Synonyms	(4S,Trans)-6-(2-Aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetic acid 1,1-dimethylethyl ester; tert-Butyl (4S,trans)-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetate; (4S,trans)-6-(2-Aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetic Acid tert-Butyl Ester; Boc-D-4-oxo-Pip-2-OH (protected form precursor); Chiral 1,3-dioxane protected amino acid ester; (S,Trans)-tert-Butyl 6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetate
EINECS	Contact for details

Quality Control

Our (4S,Trans)-1,1-Dimethylethyl-6-Aminoethyl-2,2-Dimethyl-1,3-Dioxane-4-Acetate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and stereochemical purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.