Description

(4-Methoxy-Pyridin-2-Yl)-Methyl-Carbamic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate featuring a protected carbamate group on a functionalized pyridine scaffold. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce specific molecular motifs with high regioselectivity.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used in parallel and combinatorial synthesis for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry Development: Serves as a starting material or intermediate in the scale-up and optimization of API manufacturing routes.
• Agrochemical Synthesis: Intermediate in the development of new crop protection agents and pesticides.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Used in university and institutional labs for methodological development and bioorganic chemistry studies.

Basic Information

Product Name	(4-Methoxy-Pyridin-2-Yl)-Methyl-Carbamic Acid tert-Butyl Ester
CAS No.	1104455-49-3
Molecular Formula	C12H18N2O3
Molecular Weight	238.28 g/mol
Synonyms	tert-Butyl N-methyl-N-[(4-methoxypyridin-2-yl)]carbamate; N-[(4-Methoxypyridin-2-yl)]-N-methylcarbamic acid tert-butyl ester; BOC-N-methyl-4-methoxypyridin-2-amine; 2-[(tert-Butoxycarbonyl)(methyl)amino]-4-methoxypyridine; (4-Methoxypyridin-2-yl)(methyl)carbamic acid tert-butyl ester; tert-Butyl methyl(4-methoxypyridin-2-yl)carbamate
EINECS	Contact for details

Quality Control

Every batch of (4-Methoxy-Pyridin-2-Yl)-Methyl-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including HPLC, NMR, and mass spectrometry, to ensure compliance with exacting industry standards for pharmaceutical intermediates. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.