Description

(4S)-6-Azaspiro[2.5]Octan-4-Ol CAS NO 1103501-90-1 is a high-purity, chiral spirocyclic amine alcohol building block of significant interest in advanced pharmaceutical synthesis. Its unique constrained spirocyclic structure and defined stereochemistry make it a valuable intermediate for constructing complex molecular architectures with potential biological activity. This compound is primarily utilized by research and development chemists in the pharmaceutical and biotechnology sectors for the discovery and development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder targets.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization to introduce conformational rigidity and specific stereochemistry into drug candidates.
• Chemical Biology: Serves as a scaffold or functional handle for the synthesis of chemical probes to study biological pathways and protein-ligand interactions.
• Process Chemistry: Investigated for scalable synthesis routes in the development of commercial manufacturing processes for new drugs.
• Asymmetric Synthesis: Employed as a chiral auxiliary or building block in the enantioselective synthesis of complex organic molecules.

Basic Information

Product Name	(4S)-6-Azaspiro[2.5]Octan-4-Ol
CAS No.	1103501-90-1
Molecular Formula	C7H13NO
Molecular Weight	127.18 g/mol
Synonyms	(4S)-6-Azaspiro[2.5]octan-4-ol; (4S)-6-Azaspiro[2.5]octan-4-ol; 6-Azaspiro[2.5]octan-4-ol, (4S)-; (4S)-6-Aza-spiro[2.5]octan-4-ol; (S)-6-Azaspiro[2.5]octan-4-ol; 1103501-90-1; (4S)-6-Aza-spiro[2.5]octane-4-ol
EINECS	Contact for details

Quality Control

Our (4S)-6-Azaspiro[2.5]Octan-4-Ol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot undergoes comprehensive analytical characterization, including chiral purity verification, to meet exacting customer specifications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.