Description

Thieno[2,3-B]Pyridine-3,7(4H)-Dicarboxylic Acid, 2-Amino-5,6-Dihydro-, 7-(1,1-Dimethylethyl) 3-Ethyl Ester is a high-purity, advanced pharmaceutical intermediate crucial for modern drug discovery and development. This compound serves as a key synthetic building block for constructing complex heterocyclic molecules with potential biological activity. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs) targeting various disease pathways.
• Organic Synthesis Building Block: Used in medicinal chemistry for constructing complex fused-ring systems, particularly in thienopyridine-based drug candidates.
• Research & Development: Essential for academic and industrial research programs focused on kinase inhibitors, anti-cancer agents, and other small-molecule therapeutics.
• Process Chemistry: Employed in route scouting and scale-up studies for the efficient production of target molecules.
• Agrochemical Research: Potential application as an intermediate in the development of new crop protection agents with novel modes of action.
• Material Science: Investigated as a monomer or precursor for specialty polymers and organic electronic materials due to its fused heterocyclic structure.

Basic Information

Item	Information
Product Name	Thieno[2,3-B]Pyridine-3,7(4H)-Dicarboxylic Acid, 2-Amino-5,6-Dihydro-, 7-(1,1-Dimethylethyl) 3-Ethyl Ester
CAS No.	1101857-21-9
Molecular Formula	C16H22N2O4S
Molecular Weight	338.42 g/mol
Synonyms	2-Amino-5,6-dihydrothieno[2,3-b]pyridine-3,7(4H)-dicarboxylic acid 7-tert-butyl 3-ethyl ester; 7-(tert-Butyl) 3-ethyl 2-amino-4,7-dihydro-5H-thieno[2,3-b]pyridine-3,7-dicarboxylate; tert-Butyl 2-amino-3-(ethoxycarbonyl)-5,6-dihydro-4H-thieno[2,3-b]pyridine-7-carboxylate; Ethyl 7-(tert-butoxycarbonyl)-2-amino-4,7-dihydro-5H-thieno[2,3-b]pyridine-3-carboxylate; CAS 1101857-21-9; Thienopyridine dicarboxylate ester derivative; Advanced thienopyridine intermediate.
EINECS	Contact for details

Quality Control

Our production of Thieno[2,3-B]Pyridine-3,7(4H)-Dicarboxylic Acid, 2-Amino-5,6-Dihydro-, 7-(1,1-Dimethylethyl) 3-Ethyl Ester adheres to stringent GMP-compliant protocols to ensure batch-to-batch consistency and high purity. Every lot undergoes comprehensive analytical characterization, including HPLC, NMR, and MS, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from moisture and direct light exposure. For long-term storage, consider using desiccants and storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.