Description

Ethyl 5-((tert-Butoxycarbonyl)Amino)Pyrazolo[1,5-A]Pyridine-3-Carboxylate is a high-purity, protected amino acid derivative belonging to the pyrazolopyridine class of heterocyclic compounds. This advanced pharmaceutical intermediate is critical for the synthesis of novel drug candidates, particularly in medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and agrochemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs) targeting various therapeutic areas.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) in drug discovery.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a component for constructing linkers or ligands in bifunctional degrader molecules.
• Kinase Inhibitor Synthesis: A valuable precursor for developing inhibitors targeting pyrazolopyridine-containing kinase families.
• Agrochemical Research: Employed in the discovery and development of new crop protection agents and pesticides.
• Chemical Biology Probes: Used to create tool compounds for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied for custom synthesis projects requiring this specific protected amino ester scaffold.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic and heterocyclic chemistry.

Basic Information

Item	Details
Product Name	Ethyl 5-((tert-Butoxycarbonyl)Amino)Pyrazolo[1,5-A]Pyridine-3-Carboxylate
CAS No.	1101120-33-5
Molecular Formula	C16H21N3O4
Molecular Weight	319.36 g/mol
Synonyms	Ethyl 5-(Boc-amino)pyrazolo[1,5-a]pyridine-3-carboxylate; 5-((tert-Butoxycarbonyl)amino)pyrazolo[1,5-a]pyridine-3-carboxylic acid ethyl ester; Boc-5-Amino-pyrazolo[1,5-a]pyridine-3-carboxylic acid ethyl ester; 5-(Boc-amino)pyrazolo[1,5-a]pyridine-3-carboxylic acid ethyl ester; tert-Butyl N-(3-(ethoxycarbonyl)pyrazolo[1,5-a]pyridin-5-yl)carbamate; Ethyl 5-[(tert-butoxycarbonyl)amino]pyrazolo[1,5-a]pyridine-3-carboxylate; 1101120-33-5; Boc-Protected 5-Aminopyrazolopyridine-3-carboxylate Ester
EINECS	Contact for details

Quality Control

Our Ethyl 5-((tert-Butoxycarbonyl)Amino)Pyrazolo[1,5-A]Pyridine-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment supports compliance with cGMP and ISO standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.