Description

4-Hydroxy-3-Iodo-2(1H)-Pyridinone is a halogenated pyridinone derivative, a versatile heterocyclic building block of significant interest in advanced organic synthesis and pharmaceutical research. Its core value lies in its unique molecular scaffold, which combines a metal-chelating hydroxypyridinone moiety with a reactive iodine substituent, enabling its use in the development of novel bioactive compounds and functional materials. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new molecular entities, particularly in medicinal chemistry for potential therapeutic applications.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting metal-associated diseases or requiring halogenated aromatic systems.
• Ligand for Metal Chelation: Used in the development of chelating agents for research into metal ion homeostasis, radiopharmaceuticals, or contrast agents due to the hydroxypyridinone group.
• Agrochemical Research: Employed as a building block for creating new active ingredients in crop protection products, leveraging its halogenated heterocyclic structure.
• Chemical Biology Probe: Utilized in the design and synthesis of molecular probes for studying biological processes, where the iodine atom can serve as a handle for further modification or labeling.
• Material Science: Acts as a monomer or functional additive in the development of specialized polymers or coatings with specific metal-binding properties.
• Organic Synthesis Building Block: Provides a versatile platform for cross-coupling reactions (e.g., Suzuki, Sonogashira) and further functionalization, making it valuable for constructing complex molecular architectures.

Basic Information

Product Name	4-Hydroxy-3-Iodo-2(1H)-Pyridinone
CAS No.	1100932-71-5
Molecular Formula	C5H4INO2
Molecular Weight	236.99 g/mol
Synonyms	3-Iodo-4-hydroxy-2(1H)-pyridinone; 4-Hydroxy-3-iodopyridin-2(1H)-one; 3-Iodo-4-hydroxypyridin-2(1H)-one; 4-Hydroxy-3-iodo-1H-pyridin-2-one; 2(1H)-Pyridinone, 4-hydroxy-3-iodo-; 4-Hydroxy-3-iodo-2-pyridone; 3-Iodo-4-hydroxy-1H-pyridin-2-one
EINECS	Contact for details

Quality Control

Our 4-Hydroxy-3-Iodo-2(1H)-Pyridinone is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with key specifications such as assay (HPLC), related substances, and residual solvents, available upon request. Our commitment to reliable supply and documented quality supports critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.