Description

4-(3-Chloro-5-(Trifluoromethyl)Pyridin-2-Yl)Morpholine is a high-purity, advanced pharmaceutical intermediate with a distinct heterocyclic structure. This compound matters for its critical role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new compounds with potential biological activity.

Application

• Pharmaceutical Intermediate: A crucial building block for the research and synthesis of new drug candidates, especially in kinase inhibitor and central nervous system (CNS) therapeutic programs.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging the pyridine-morpholine scaffold for bioactivity.
• Chemical Synthesis: Serves as a versatile precursor for further functionalization in medicinal chemistry and material science applications.
• Ligand & Catalyst Development: Employed in the creation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Life Sciences Research: Utilized in academic and industrial laboratories for biochemical and pharmacological studies.

Basic Information

Product Name	4-(3-Chloro-5-(Trifluoromethyl)Pyridin-2-Yl)Morpholine
CAS No.	1100767-03-0
Molecular Formula	C10H10ClF3N2O
Molecular Weight	266.65 g/mol
Synonyms	2-Morpholino-3-chloro-5-(trifluoromethyl)pyridine; 3-Chloro-5-(trifluoromethyl)-2-(morpholin-4-yl)pyridine; 4-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]morpholine; Morpholine, 4-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-; 1100767-03-0; 4-(3-Chloro-5-trifluoromethyl-pyridin-2-yl)-morpholine
EINECS	Contact for details

Quality Control

Our 4-(3-Chloro-5-(Trifluoromethyl)Pyridin-2-Yl)Morpholine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development and commercial projects requiring compliance with cGMP and ICH Q7 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.