Description

n-(3-(Imidazo[1,2-A]Pyridin-2-Yl)Phenyl)-8-Methoxy-2-Oxo-2H-Chromene-3-Carboxamide CAS NO 1100353-03-4 is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly in areas requiring sophisticated molecular scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of target drug candidates for preclinical and clinical research.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• API Development: Employed in the process development and scale-up of new chemical entities (NCEs), especially those targeting neurological or oncological pathways.
• Biochemical Tool Compound: Acts as a reference standard or a probe molecule in biochemical and pharmacological assays to study specific biological mechanisms.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.
• Academic Research: Utilized in university and institutional labs for fundamental organic synthesis methodology and heterocyclic chemistry studies.

Basic Information

Product Name	n-(3-(Imidazo[1,2-A]Pyridin-2-Yl)Phenyl)-8-Methoxy-2-Oxo-2H-Chromene-3-Carboxamide
CAS No.	1100353-03-4
Molecular Formula	C24H17N3O4
Molecular Weight	411.41 g/mol
Synonyms	8-Methoxy-2-oxo-N-[3-(imidazo[1,2-a]pyridin-2-yl)phenyl]-2H-chromene-3-carboxamide; 8-Methoxy-2-oxo-N-[3-(imidazo[1,2-a]pyridin-2-yl)phenyl]-2H-1-benzopyran-3-carboxamide; 1100353-03-4; UNII-9Q8FQ8W8VK; 9Q8FQ8W8VK; SCHEMBL21807727; BCP31033; AKOS040759176.
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency suitable for research and development use. Certificates of Analysis (COA) detailing results from HPLC, NMR, and mass spectrometry are available upon request. Our quality commitment supports compliance with the standards expected in pharmaceutical R&D and cGMP-oriented synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.