Description

(S)-Methyl Pyrrolidine-3-Carboxylate Hydrochloride is a high-purity chiral building block and intermediate of significant importance in modern synthetic chemistry. Its value lies in its stereochemically defined pyrrolidine scaffold, which is a privileged structure in medicinal chemistry for constructing bioactive molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries engaged in the development of novel active ingredients, particularly those targeting the central nervous system.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of drug candidates, especially those containing proline or pyrrolidine motifs.
• API Development: Used in the research and process development of Active Pharmaceutical Ingredients (APIs) with specific stereochemical requirements.
• Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, or insecticides with enhanced efficacy.
• Ligand and Catalyst Preparation: Utilized in the preparation of chiral ligands and organocatalysts for asymmetric synthesis.
• Chemical Biology Research: Employed in the design and synthesis of molecular probes and tool compounds for biological target investigation.
• Peptidomimetics: A crucial component for constructing peptidomimetic compounds that mimic the structure and function of natural peptides.

Basic Information

Product Name	(S)-Methyl Pyrrolidine-3-Carboxylate Hydrochloride
CAS No.	1099646-61-3
Molecular Formula	C7H14ClNO2
Molecular Weight	179.65 g/mol
Synonyms	(S)-Methyl 3-Pyrrolidinecarboxylate Hydrochloride; (3S)-3-(Methoxycarbonyl)pyrrolidine Hydrochloride; Methyl (S)-3-Pyrrolidinecarboxylate HCl; L-Proline methyl ester hydrochloride (isomer); (S)-3-Carbomethoxypyrrolidine Hydrochloride; (S)-1-Methyl pyrrolidine-3-carboxylic acid hydrochloride; Pyrrolidine-3-carboxylic acid, methyl ester, hydrochloride, (3S)-
EINECS	Contact for details

Quality Control

Our (S)-Methyl Pyrrolidine-3-Carboxylate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.