Description

2,6-Dichloro-3-Fluoro-5-(Trifluoromethyl)Pyridine is a high-purity, multi-halogenated pyridine derivative serving as a critical advanced intermediate in modern chemical synthesis. Its value lies in the unique reactivity imparted by its specific halogen pattern, enabling precise molecular construction for complex target molecules. This compound is essential for R&D and production chemists in the pharmaceutical and agrochemical industries, where it is used to build active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of novel small-molecule drugs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Material Science Research: Serves as a precursor for creating specialized ligands, functional polymers, and liquid crystal materials.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions due to its halogen substituents.
• Nucleophilic Aromatic Substitution: The electron-deficient pyridine ring facilitates selective substitution reactions for further functionalization.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical manufacturing.

Basic Information

Product Name	2,6-Dichloro-3-Fluoro-5-(Trifluoromethyl)Pyridine
CAS No.	1099598-11-4
Molecular Formula	C6HCl2F4N
Molecular Weight	233.98 g/mol
Synonyms	2,6-Dichloro-3-fluoro-5-(trifluoromethyl)pyridine; 5-(Trifluoromethyl)-2,6-dichloro-3-fluoropyridine; Pyridine, 2,6-dichloro-3-fluoro-5-(trifluoromethyl)-; 3-Fluoro-2,6-dichloro-5-trifluoromethylpyridine; 2,6-Dichloro-3-fluoro-5-trifluoromethylpyridine
EINECS	Contact for details

Quality Control

Our 2,6-Dichloro-3-Fluoro-5-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for use in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reactive metals. Due to its fluoride/strong alkali chemical property, ensure storage areas are separate from bases and sources of moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Purity (GC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤1.0%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.