Description

5-Bromo-2,4-Bis(Trifluoromethyl)Pyridine is a high-value, multi-functional halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both bromine and trifluoromethyl groups, makes it an indispensable intermediate for introducing specific steric and electronic properties into target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and antiviral applications.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl groups enhance biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a backbone for creating specialized ligands in transition metal catalysis and organocatalysis, enabling novel reaction pathways.
• Material Science Research: Employed in the synthesis of advanced organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its electron-deficient aromatic system.
• Fluorinated Compound Library: A valuable scaffold for medicinal chemistry to build diverse compound libraries for high-throughput screening (HTS) in drug discovery programs.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke molecules for client projects.

Basic Information

Product Name	5-Bromo-2,4-Bis(Trifluoromethyl)Pyridine
CAS No.	1099598-05-6
Molecular Formula	C8H2BrF6N
Molecular Weight	305.00 g/mol
Synonyms	2,4-Bis(trifluoromethyl)-5-bromopyridine; 5-Bromo-2,4-di(trifluoromethyl)pyridine; 5-Bromo-α,α,α,α',α',α'-hexafluoro-2,4-lutidine; Pyridine, 5-bromo-2,4-bis(trifluoromethyl)-; 5-Bromo-2,4-bis(trifluoromethyl)pyridine
EINECS	Contact for details

Quality Control

Our 5-Bromo-2,4-Bis(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for sensitive R&D and scale-up processes. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.