Description

3,6-Difluoro-2-(trifluoromethyl)pyridine is a high-value fluorinated pyridine derivative, a key building block in advanced organic synthesis. Its unique structure, featuring multiple fluorine atoms and a trifluoromethyl group, is engineered to impart enhanced metabolic stability, lipophilicity, and bioavailability to target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors, antiviral agents, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms improve efficacy and environmental profile.
• Material Science Precursor: Serves as a building block for advanced materials, including liquid crystals, organic semiconductors, and functional polymers.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new reactions, catalysis, and the synthesis of complex fluorinated heterocycles.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects, supporting scale-up from milligram to kilogram quantities for clinical and commercial applications.

Basic Information

Product Name	3,6-Difluoro-2-(trifluoromethyl)pyridine
CAS No.	1099597-92-8
Molecular Formula	C6H2F5N
Molecular Weight	183.08 g/mol
Synonyms	2-(Trifluoromethyl)-3,6-difluoropyridine; 3,6-Difluoro-2-trifluoromethylpyridine; Pyridine, 3,6-difluoro-2-(trifluoromethyl)-; 1099597-92-8
EINECS	Contact for details

Quality Control

We supply 3,6-Difluoro-2-(trifluoromethyl)pyridine in high-purity grades suitable for demanding R&D and scale-up applications. Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with industry standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (GC)	≥ 98.0% (Premium Grade)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.