Description

6-Methyl-2,3-Bis-(Trifluoromethyl)Pyridine is a high-value, multi-fluorinated pyridine derivative that serves as a critical building block in advanced chemical synthesis. Its unique structure, featuring two trifluoromethyl groups, imparts significant lipophilicity, metabolic stability, and electron-withdrawing properties, making it indispensable for creating novel compounds with enhanced performance. This intermediate is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for sophisticated ligands in catalysis, especially in cross-coupling reactions critical for fine chemical manufacturing.
• Material Science Research: Employed in the synthesis of specialty polymers, liquid crystals, and electronic materials that require fluorinated aromatic components.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses serving the life sciences industry.

Basic Information

Product Name	6-Methyl-2,3-Bis-(Trifluoromethyl)Pyridine
CAS No.	1099597-76-8
Molecular Formula	C9H5F6N
Molecular Weight	241.13 g/mol
Synonyms	2,3-Bis(trifluoromethyl)-6-methylpyridine; 6-Methyl-2,3-di(trifluoromethyl)pyridine; 2,3-Bis(trifluoromethyl)-6-picoline; 6-Methyl-2,3-bis(trifluoromethyl)pyridine; Pyridine, 2,3-bis(trifluoromethyl)-6-methyl-; 2,3-Bis(trifluoromethyl)-6-methylpyridine
EINECS	Contact for details

Quality Control

Every batch of 6-Methyl-2,3-Bis-(Trifluoromethyl)Pyridine is produced under strict quality management protocols. We employ advanced analytical techniques including GC, HPLC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.