Description

2-Bromo-6-Phenylpyridine n-Oxide CAS NO 1097732-14-3 is a high-value brominated heterocyclic building block characterized by its pyridine N-oxide functional group. This compound is essential for facilitating advanced cross-coupling reactions and serving as a key precursor in the synthesis of complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for drug discovery and fine chemical manufacturing.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly in kinase inhibitor research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated structure for further functionalization.
• Ligand Precursor: Serves as a starting material for the preparation of specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the creation of organic electronic materials, such as OLEDs and conductive polymers, due to its conjugated system.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions to form biaryl and other complex structures.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein interactions.

Basic Information

Product Name	2-Bromo-6-Phenylpyridine n-Oxide
CAS No.	1097732-14-3
Molecular Formula	C11H8BrNO
Molecular Weight	250.09 g/mol
Synonyms	2-Bromo-6-phenylpyridine 1-oxide; 6-Phenyl-2-bromopyridine N-oxide; 2-Bromo-6-phenylpyridine N-oxide; Pyridine, 2-bromo-6-phenyl-, 1-oxide; (2-Bromo-6-pyridinyl)benzene N-oxide; 1097732-14-3; 2-Br-6-PhPyO
EINECS	Contact for details

Quality Control

Our 2-Bromo-6-Phenylpyridine n-Oxide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.