Description

1-Pyridin-2-Yl-1H-Pyrazole-4-Sulfonyl Chloride is a high-purity, reactive sulfonyl chloride derivative used as a critical building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring a versatile electrophile to introduce the pyridyl-pyrazole-sulfonyl moiety into target molecules. It is primarily utilized in the development of active pharmaceutical ingredients (APIs), agrochemicals, and functional materials, where precise molecular architecture is paramount.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor research and other small-molecule therapeutics.
• Agrochemical Synthesis: Used to construct advanced herbicide and pesticide molecules, leveraging its bioactive heterocyclic scaffold.
• Chemical Biology & Proteomics: Serves as a reactive handle for labeling, cross-linking, or modifying proteins and other biomolecules.
• Material Science Research: Employed in the creation of specialized polymers, ligands for catalysis, and organic electronic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for client-specific research and scale-up projects.

Basic Information

Product Name	1-Pyridin-2-Yl-1H-Pyrazole-4-Sulfonyl Chloride
CAS No.	1097223-12-5
Molecular Formula	C8H6ClN3O2S
Molecular Weight	243.67 g/mol
Synonyms	1-(Pyridin-2-yl)-1H-pyrazole-4-sulfonyl chloride; 1-(2-Pyridinyl)-1H-pyrazole-4-sulfonyl chloride; 1H-Pyrazole-4-sulfonyl chloride, 1-(2-pyridinyl)-; 1097223-12-5; 2-(4-Sulfonylchloridopyrazol-1-yl)pyridine
EINECS	Contact for details

Quality Control

Our 1-Pyridin-2-Yl-1H-Pyrazole-4-Sulfonyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of research and development as well as scale-up manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.