Description

5-Chloro-4-(Trifluoromethyl)Pyridin-2-Amine Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a distinct trifluoromethylpyridine core structure. This compound is valued for its role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the agrochemical and pharmaceutical research sectors. It is essential for medicinal chemists and process development scientists working on fluorinated heterocyclic compounds for drug discovery and crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new drug candidates, especially those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of next-generation pesticides and herbicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Chemical Research & Development: Serves as a versatile precursor for further functionalization in organic synthesis and material science projects.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for catalysis and molecular recognition studies.

Basic Information

Product Name	5-Chloro-4-(Trifluoromethyl)Pyridin-2-Amine Hydrochloride
CAS No.	1095824-77-3
Molecular Formula	C7H5ClF3N2•HCl
Molecular Weight	263.48 g/mol
Synonyms	2-Amino-5-chloro-4-(trifluoromethyl)pyridine hydrochloride; 5-Chloro-4-(trifluoromethyl)-2-pyridinamine hydrochloride; 5-Chloro-4-trifluoromethylpyridin-2-ylamine hydrochloride; 2-Pyridinamine, 5-chloro-4-(trifluoromethyl)-, hydrochloride (1:1); 1095824-77-3 (CAS)
EINECS	Contact for details

Quality Control

Our 5-Chloro-4-(Trifluoromethyl)Pyridin-2-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.