Description

Carbamic Acid, n-[1-[5-[[[5-Chloro-4-(Trifluoromethyl)-2-Pyridinyl]Amino]Carbonyl]-2-Thiazolyl]Ethyl]-, Phenylmethyl Ester is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, particularly in programs targeting specific enzyme inhibition. It is primarily utilized by pharmaceutical manufacturers and contract research organizations (CROs) engaged in the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the multi-step synthesis of potential drug candidates, especially in oncology and antiviral research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes within drug discovery pipelines.
• API Synthesis: Integral in the production route for active pharmaceutical ingredients that incorporate complex heterocyclic scaffolds.
• Biochemical Tool Compound: May be utilized in vitro as a probe to study specific biological pathways and mechanisms of action.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP-scale production.

Basic Information

Product Name	Carbamic Acid, n-[1-[5-[[[5-Chloro-4-(Trifluoromethyl)-2-Pyridinyl]Amino]Carbonyl]-2-Thiazolyl]Ethyl]-, Phenylmethyl Ester
CAS No.	1095823-54-3
Molecular Formula	C20H15ClF3N3O3S
Molecular Weight	469.86 g/mol
Synonyms	Benzyl N-[1-[5-[[[5-chloro-4-(trifluoromethyl)pyridin-2-yl]amino]carbonyl]-1,3-thiazol-2-yl]ethyl]carbamate; (S)-Benzyl 1-(5-((5-chloro-4-(trifluoromethyl)pyridin-2-yl)carbamoyl)thiazol-2-yl)ethylcarbamate; Carbamic acid, N-[1-[5-[[[5-chloro-4-(trifluoromethyl)-2-pyridinyl]amino]carbonyl]-2-thiazolyl]ethyl]-, phenylmethyl ester; UNII-9J8F1106VU; 9J8F1106VU; Benzyl (1-(5-((5-chloro-4-(trifluoromethyl)pyridin-2-yl)carbamoyl)thiazol-2-yl)ethyl)carbamate
EINECS	Contact for details

Quality Control

Our Carbamic Acid, n-[1-[5-[[[5-Chloro-4-(Trifluoromethyl)-2-Pyridinyl]Amino]Carbonyl]-2-Thiazolyl]Ethyl]-, Phenylmethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided and can be tailored to support regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.