Description

5-Chloro-4-(Trifluoromethyl)Pyridin-2-Amine CAS NO 1095823-39-4 is a high-value, multi-functional pyridine derivative characterized by its chloro and trifluoromethyl substituents, which confer unique reactivity and physicochemical properties. This compound serves as a critical advanced pharmaceutical intermediate and agrochemical building block, enabling the synthesis of novel active ingredients. It is essential for R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new compounds with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used as a core building block for novel herbicides, fungicides, and insecticides, leveraging the trifluoromethyl group for improved efficacy and environmental profile.
• Material Science Research: Employed in the synthesis of functionalized ligands for catalysis and as a precursor for advanced organic electronic materials.
• Chemical Biology & Proteomics: Serves as a versatile scaffold for designing molecular probes and enzyme inhibitors in biochemical research.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up production under cGMP or ISO standards.

Basic Information

Product Name	5-Chloro-4-(Trifluoromethyl)Pyridin-2-Amine
CAS No.	1095823-39-4
Molecular Formula	C6H4ClF3N2
Molecular Weight	196.56 g/mol
Synonyms	2-Amino-5-chloro-4-(trifluoromethyl)pyridine; 5-Chloro-4-(trifluoromethyl)-2-pyridinamine; 4-(Trifluoromethyl)-5-chloropyridin-2-amine; 1095823-39-4; 5-Chloro-4-trifluoromethylpyridin-2-ylamine
EINECS	Contact for details

Quality Control

Our production of 5-Chloro-4-(Trifluoromethyl)Pyridin-2-Amine adheres to stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all critical specifications. We support customer audits and can supply material that meets the requirements for use in regulated environments under appropriate quality agreements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong acids, strong bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Any single unknown impurity	≤0.5%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.