Description

4-Ethynylpyridin-2-Amine is a high-purity, functionalized pyridine derivative featuring both an amine and an ethynyl group, making it a versatile and valuable building block in advanced organic synthesis. Its bifunctional nature allows for selective modifications, enabling the construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, particularly for developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used to develop new active ingredients for crop protection with enhanced efficacy and selectivity.
• Ligand Synthesis: Serves as a building block for creating sophisticated ligands used in catalysis and metal-organic frameworks (MOFs).
• Polymer & Material Science: Incorporated into monomers for the production of specialty polymers with tailored electronic or mechanical properties.
• Chemical Biology Probes: Utilized in click chemistry applications to create labeled probes for studying biological processes.
• Academic & R&D: A fundamental reagent for exploratory organic synthesis and methodology development in research laboratories.

Basic Information

Product Name	4-Ethynylpyridin-2-Amine
CAS No.	1094679-27-2
Molecular Formula	C7H6N2
Molecular Weight	118.14 g/mol
Synonyms	2-Amino-4-ethynylpyridine; 4-Ethynyl-2-pyridinamine; 4-Ethynylpyridin-2-ylamine; 2-Pyridinamine, 4-ethynyl-; 4-Ethynyl-2-aminopyridine
EINECS	Contact for details

Quality Control

Our 4-Ethynylpyridin-2-Amine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications. We adhere to cGMP principles where applicable to support our customers in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.