Description

1-(6-Chloro-3-Nitropyridin-2-Yl)Azepane is a high-purity, advanced pharmaceutical intermediate featuring a unique heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Used for scaling up synthetic routes and optimizing manufacturing processes for new chemical entities (NCEs).
• Agrochemical Synthesis: Potential intermediate in the development of advanced crop protection agents and pesticides.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical and agrochemical innovation.

Basic Information

Product Name	1-(6-Chloro-3-Nitropyridin-2-Yl)Azepane
CAS No.	1094400-01-7
Molecular Formula	C11H14ClN3O2
Molecular Weight	255.70 g/mol
Synonyms	Azepane, 1-(6-chloro-3-nitro-2-pyridinyl)-; 1-(6-Chloro-3-nitropyridin-2-yl)azepane; 2-(Azepan-1-yl)-6-chloro-3-nitropyridine; 6-Chloro-3-nitro-2-(azepan-1-yl)pyridine; 1-(6-Chloro-3-nitro-2-pyridinyl)hexamethyleneimine; Hexamethyleneimine, 1-(6-chloro-3-nitro-2-pyridinyl)-
EINECS	Contact for details

Quality Control

Our 1-(6-Chloro-3-Nitropyridin-2-Yl)Azepane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.