Description

(2-Chloro-Pyridin-3-Yl)-(4-Hydroxymethyl-Piperidin-1-Yl)-Methanone is a high-purity, advanced pharmaceutical intermediate of significant commercial interest. This compound is valued for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new therapeutic agents and high-value products.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its heterocyclic structure.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry and process chemistry optimization in laboratory settings.
• Ligand and Catalyst Development: Employed in the creation of specialized ligands for metal-catalyzed reactions and asymmetric synthesis.
• Custom Synthesis Projects: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke fine chemicals.

Basic Information

Product Name	(2-Chloro-Pyridin-3-Yl)-(4-Hydroxymethyl-Piperidin-1-Yl)-Methanone
CAS No.	1094301-19-5
Molecular Formula	C12H15ClN2O2
Molecular Weight	254.71 g/mol
Synonyms	1-(2-Chloropyridine-3-carbonyl)-4-(hydroxymethyl)piperidine; (2-Chloro-3-pyridinyl)[4-(hydroxymethyl)-1-piperidinyl]methanone; 2-Chloro-N-(4-(hydroxymethyl)piperidin-1-yl)nicotinamide; 1094301-19-5; AKOS025310193; 2-Chloro-3-((4-(hydroxymethyl)piperidin-1-yl)carbonyl)pyridine
EINECS	Contact for details

Quality Control

Our (2-Chloro-Pyridin-3-Yl)-(4-Hydroxymethyl-Piperidin-1-Yl)-Methanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.