Description

1,3,4,6-Tetra-o-Acetyl-n-Azidoacetylmannosamine is a key protected monosaccharide derivative, specifically an azido-functionalized mannosamine, widely used as a critical building block in chemical synthesis. Its core value lies in its dual functionality, where the azido group serves as a versatile handle for click chemistry reactions, enabling the efficient construction of complex glycoconjugates and labeled biomolecules. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors, particularly for developing novel glycotherapeutics, vaccines, and molecular probes.

Application

• Glycoconjugate Synthesis: A pivotal intermediate for the chemical and chemoenzymatic synthesis of complex oligosaccharides, glycopeptides, and glycolipids.
• Click Chemistry Substrate: The azido group enables efficient, high-yield Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC) for bioconjugation and labeling applications.
• Pharmaceutical Intermediate: Used in the research and development of novel glycoprotein-based drugs, including antibody-drug conjugates (ADCs) and antiviral agents.
• Vaccine Development: Serves as a building block for synthesizing carbohydrate antigens used in conjugate vaccine candidates against bacterial pathogens.
• Molecular Probe & Diagnostic Agent Production: Facilitates the creation of fluorescently or chemically tagged sugars for studying glycosylation pathways and for diagnostic assays.
• Chemical Biology Research: A fundamental tool for metabolic glycoengineering, allowing the introduction of azido tags into cellular glycans for subsequent visualization or capture.
• Biomaterial Functionalization: Used to modify surfaces and polymers with sugar moieties to create bioactive materials for tissue engineering and biosensing.

Basic Information

Product Name	1,3,4,6-Tetra-o-Acetyl-n-Azidoacetylmannosamine
CAS No.	1094268-54-8
Molecular Formula	C16H22N4O10
Molecular Weight	430.37 g/mol
Synonyms	2-Azidoacetamido-1,3,4,6-tetra-O-acetyl-2-deoxy-α/β-D-mannopyranose; 2-Deoxy-2-[(azidoacetyl)amino]-D-mannose tetraacetate; Ac4ManNAz; Tetraacetylated N-azidoacetylmannosamine; N-Azidoacetylmannosamine tetraacetate; 1,3,4,6-Tetra-O-acetyl-2-azidoacetamido-2-deoxy-D-mannopyranose; Peracetylated ManNAz
EINECS	Contact for details

Quality Control

Our 1,3,4,6-Tetra-o-Acetyl-n-Azidoacetylmannosamine is produced under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research and development applications. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and MS, to confirm identity, purity, and the absence of critical impurities. A detailed Certificate of Analysis (COA) documenting all test results is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be handled under an inert atmosphere when appropriate for prolonged use to ensure long-term stability. Keep container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.