Description

6-Chloro-2-Fluoro-Nicotinic Acid Methyl Ester is a high-purity fluorinated pyridine derivative, a critical building block in modern organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for research chemists and process development scientists working on active ingredients, especially those targeting central nervous system disorders and novel crop protection agents.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in neurology and oncology research.
• Agrochemical Synthesis: Used in the production of advanced herbicides and insecticides, leveraging the fluorine atom for enhanced bioactivity and environmental stability.
• Material Science Research: Serves as a precursor for functionalized ligands and organic electronic materials.
• Chemical Biology: Employed in the synthesis of probes and labeled compounds for biochemical studies.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes under cGMP conditions.

Basic Information

Product Name	6-Chloro-2-Fluoro-Nicotinic Acid Methyl Ester
CAS No.	1093880-34-2
Molecular Formula	C7H5ClFNO2
Molecular Weight	189.57 g/mol
Synonyms	Methyl 6-Chloro-2-fluoronicotinate; 2-Fluoro-6-chloronicotinic Acid Methyl Ester; 6-Chloro-2-fluoropyridine-3-carboxylic Acid Methyl Ester; 3-Pyridinecarboxylic Acid, 6-Chloro-2-fluoro-, Methyl Ester; Methyl 6-Chloro-2-fluoropyridine-3-carboxylate; 1093880-34-2
EINECS	Contact for details

Quality Control

Our 6-Chloro-2-Fluoro-Nicotinic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. The compound is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.