Description

1H-Pyrrolo[2,3-B]Pyridine, 3-Iodo-5-(1-Methyl-1H-Pyrazol-4-Yl)- is a high-value, halogenated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceutical agents and agrochemicals, enabling the construction of complex molecular architectures. It is primarily needed by research and development chemists in the pharmaceutical, biotechnology, and agrochemical industries for drug discovery programs and the synthesis of active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of kinase inhibitors and other targeted therapeutic small molecules.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Chemical Biology: Employed as a molecular probe or a tagged scaffold for studying protein-ligand interactions and biological pathways.
• Material Science: Potential building block for creating organic electronic materials and advanced polymers with specific optoelectronic properties.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create diverse biaryl structures.
• Library Synthesis: A valuable reagent for generating focused compound libraries in high-throughput screening for drug discovery.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine, 3-Iodo-5-(1-Methyl-1H-Pyrazol-4-Yl)-
CAS No.	1093676-98-2
Molecular Formula	C11H9IN4
Molecular Weight	324.12 g/mol
Synonyms	3-Iodo-5-(1-methyl-1H-pyrazol-4-yl)-1H-pyrrolo[2,3-b]pyridine; 3-Iodo-5-(1-methylpyrazol-4-yl)-7-azaindole; 5-(1-Methyl-1H-pyrazol-4-yl)-3-iodo-1H-pyrrolo[2,3-b]pyridine; 3-Iodo-5-(1-methyl-1H-pyrazol-4-yl)-7-azaindole; 1H-Pyrrolo[2,3-b]pyridine, 3-iodo-5-(1-methyl-1H-pyrazol-4-yl)-; 1093676-98-2; 3-Iodo-5-(1-methylpyrazol-4-yl)-1H-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide Certificates of Analysis (COA) with each batch, detailing purity and identity confirmation. Quality is assured through analytical techniques including HPLC, NMR, and mass spectrometry. For custom synthesis or specific purity requirements (e.g., >98% HPLC), please contact our technical team to discuss your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light). For long-term storage, consider storage under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.