Description

4-Bromo-2-Iodo-Benzoic Acid Methyl Ester is a high-purity halogenated aromatic building block of significant importance in advanced organic synthesis. This compound serves as a versatile intermediate for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the life sciences and specialty chemical industries for applications requiring precise functionalization and coupling reactions.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing complex halogen-substituted aromatic rings.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the bromo and iodo substituents enable further cross-coupling transformations.
• Material Science Research: Serves as a monomer or building block for creating specialized polymers and liquid crystals with unique electronic or optical properties.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions due to the presence of both bromo and iodo leaving groups with different reactivities.
• Ligand and Catalyst Development: Employed in the preparation of novel ligands for metal-organic frameworks (MOFs) or homogeneous catalysis.
• Chemical Biology Probes: Useful for synthesizing tagged molecules or probes for biochemical and diagnostic research applications.

Basic Information

Product Name	4-Bromo-2-Iodo-Benzoic Acid Methyl Ester
CAS No.	1093418-75-7
Molecular Formula	C8H6BrIO2
Molecular Weight	340.94 g/mol
Synonyms	Methyl 4-Bromo-2-iodobenzoate; Benzoic acid, 4-bromo-2-iodo-, methyl ester; 4-Bromo-2-iodobenzoic acid methyl ester; Methyl 4-bromo-2-iodobenzoate; 2-Iodo-4-bromobenzoic acid methyl ester
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Iodo-Benzoic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures the material meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.