Description

n-[5-(4-Cyanophenyl)-1H-Pyrrolo[2,3-B]Pyridin-3-Yl]-3-Pyridinecarboxamide is a high-purity, advanced pharmaceutical intermediate designed for research and development in targeted drug discovery. This compound is of significant interest for its role as a key building block in the synthesis of novel kinase inhibitors and other biologically active molecules. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic research institutions focused on oncology, immunology, and metabolic disease therapeutics.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of small molecule kinase inhibitors for targeted cancer therapies.
• Biochemical Research: Used as a reference standard or a probe compound in enzymatic assays and high-throughput screening (HTS) campaigns.
• Drug Discovery & Development: Serves as a core scaffold for medicinal chemistry optimization programs aimed at improving potency, selectivity, and pharmacokinetic properties.
• Academic Research: Employed in university and institutional labs for studying structure-activity relationships (SAR) and signal transduction pathways.
• Custom Synthesis: A starting material for the contract development and manufacturing (CDMO) of novel active pharmaceutical ingredients (APIs).

Basic Information

Product Name	n-[5-(4-Cyanophenyl)-1H-Pyrrolo[2,3-B]Pyridin-3-Yl]-3-Pyridinecarboxamide
CAS No.	1093222-27-5
Molecular Formula	C20H13N5O
Molecular Weight	339.35 g/mol
Synonyms	3-Pyridinecarboxamide, N-[5-(4-cyanophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]-; N-(5-(4-Cyanophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl)nicotinamide; 1093222-27-5; Pyrrolopyridine nicotinamide derivative; Kinase inhibitor intermediate; 5-(4-Cyanophenyl)-3-(nicotinamido)-1H-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our n-[5-(4-Cyanophenyl)-1H-Pyrrolo[2,3-B]Pyridin-3-Yl]-3-Pyridinecarboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.