Description

6-(2-Fluoropyridin-3-Yl)-9-(Tetrahydro-2H-Pyran-2-Yl)-9H-Purine is a high-purity, advanced pharmaceutical intermediate designed for research and development in modern drug discovery. This compound is a key building block in the synthesis of targeted small molecule therapeutics, particularly those acting on kinase pathways. It is essential for medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries seeking to develop novel oncology and anti-inflammatory agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potent kinase inhibitors and other biologically active purine derivatives.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization campaigns to develop new drug candidates.
• Process Chemistry & Scale-Up: Serves as a key raw material for process route development and cGMP manufacturing of active pharmaceutical ingredients (APIs).
• Biochemical Tool Compound: Can be utilized in biochemical assays to study enzyme function and for target validation in early-stage drug discovery.
• Custom Synthesis Building Block: Employed by fine chemical suppliers for the custom synthesis of complex, fluorinated heterocyclic compounds for client-specific projects.

Basic Information

Product Name	6-(2-Fluoropyridin-3-Yl)-9-(Tetrahydro-2H-Pyran-2-Yl)-9H-Purine
CAS No.	1093101-52-0
Molecular Formula	C15H14FN5O
Molecular Weight	299.31 g/mol
Synonyms	9H-Purine, 6-(2-fluoro-3-pyridinyl)-9-(tetrahydro-2H-pyran-2-yl)-; 6-(2-Fluoropyridin-3-yl)-9-(tetrahydro-2H-pyran-2-yl)-9H-purine; 6-(2-Fluoro-3-pyridyl)-9-(tetrahydropyran-2-yl)purine; THP-Protected Fluoropyridinyl Purine; 1093101-52-0; 6-(2-Fluoropyridin-3-yl)-9-(oxan-2-yl)purine
EINECS	Contact for details

Quality Control

Our production of 6-(2-Fluoropyridin-3-Yl)-9-(Tetrahydro-2H-Pyran-2-Yl)-9H-Purine adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and KF for moisture content, to ensure consistency and reliability. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support development under quality agreements and can supply material suitable for use in GMP-regulated environments upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.