Description

6-Bromo-[1,2,4)triazolo[4,3-a]pyridine-3-thiol is a high-value heterocyclic building block featuring a fused triazolopyridine core functionalized with bromine and thiol groups. This compound matters for its unique reactivity profile, enabling the synthesis of complex molecules in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the life sciences sector for constructing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides due to its bioactive heterocyclic scaffold.
• Material Science: Serves as a precursor for ligands in catalysis or for creating functionalized polymers and advanced organic materials.
• Chemical Biology: Employed as a probe or linker in bioconjugation chemistry, leveraging the reactivity of the thiol and bromo substituents.
• Academic Research: A valuable reagent for methodological studies in organic synthesis, including cross-coupling and heterocycle functionalization reactions.

Basic Information

Product Name	6-Bromo-[1,2,4)triazolo[4,3-a]pyridine-3-thiol
CAS No.	1093092-64-8
Molecular Formula	C6H4BrN3S
Molecular Weight	230.09 g/mol
Synonyms	6-Bromo-[1,2,4]triazolo[4,3-a]pyridine-3-thiol; 6-Bromo-3-mercapto-[1,2,4]triazolo[4,3-a]pyridine; 3-Mercapto-6-bromo-[1,2,4]triazolo[4,3-a]pyridine; 6-Bromo-1,2,4-triazolo[4,3-a]pyridine-3-thiol; 1093092-64-8; 6-Bromo-3-thioxo-3,4-dihydro-[1,2,4]triazolo[4,3-a]pyridine (tautomeric form); 6-Bromo-[1,2,4]triazolo[4,3-a]pyridine-3(4H)-thione
EINECS	Contact for details

Quality Control

Our 6-Bromo-[1,2,4)triazolo[4,3-a]pyridine-3-thiol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and development applications. Comprehensive Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider under an inert atmosphere such as nitrogen or argon. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.