Description

1-(2-Cyano-Phenyl)-Cyclopropanecarboxylic Acid Methyl Ester is a versatile and high-value chemical intermediate characterized by its unique cyclopropane ring fused with a cyano-substituted aromatic system. This compound is critical for the synthesis of complex molecules, offering a strategic building block for introducing constrained three-dimensional geometry and functional handles for further derivatization. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Ligand and Catalyst Development: Serves as a sophisticated scaffold for constructing novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of specialty polymers and advanced organic electronic materials due to its rigid molecular structure.
• Chemical Biology Probes: Utilized as a building block for creating molecular probes and tags to study biological processes and protein interactions.
• Custom Synthesis and Contract Manufacturing: A critical component for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	1-(2-Cyano-Phenyl)-Cyclopropanecarboxylic Acid Methyl Ester
CAS No.	1092794-06-3
Molecular Formula	C12H11NO2
Molecular Weight	201.22 g/mol
Synonyms	Methyl 1-(2-cyanophenyl)cyclopropanecarboxylate; 1-(2-Cyanophenyl)cyclopropanecarboxylic acid methyl ester; Cyclopropanecarboxylic acid, 1-(2-cyanophenyl)-, methyl ester; Methyl 1-(2-cyanophenyl)cyclopropane-1-carboxylate; 1-(o-Cyanophenyl)cyclopropanecarboxylic Acid Methyl Ester; 2-(Methoxycarbonyl)cyclopropyl)benzonitrile
EINECS	Contact for details

Quality Control

Our 1-(2-Cyano-Phenyl)-Cyclopropanecarboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified for high-purity grades. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥97.0% (Area Percent)
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5% w/w
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.