Description

2-Chloromethyl-3-Methyl-3H-Imidazo[4,5-B]Pyridine is a versatile and high-value heterocyclic building block, primarily used in advanced pharmaceutical synthesis. Its molecular structure makes it a critical intermediate for the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex nitrogen-containing heterocycles. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to create new molecular entities with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that leverage its imidazopyridine core.
• Fine Chemical Synthesis: Serves as a versatile building block for creating specialty chemicals, ligands, and catalysts.
• Material Science: Potential applications in the development of organic electronic materials and advanced polymers.
• Bioconjugation & Probe Development: The reactive chloromethyl group allows for functionalization, useful in creating biochemical probes and diagnostic agents.

Basic Information

Product Name	2-Chloromethyl-3-Methyl-3H-Imidazo[4,5-B]Pyridine
CAS No.	1092697-36-3
Molecular Formula	C9H8ClN3
Molecular Weight	193.63 g/mol
Synonyms	3-Methyl-2-(chloromethyl)-3H-imidazo[4,5-b]pyridine; 2-(Chloromethyl)-3-methyl-3H-imidazo[4,5-b]pyridine; 3H-Imidazo[4,5-b]pyridine, 2-(chloromethyl)-3-methyl-; 1092697-36-3; 2-Chloromethyl-3-methylimidazo[4,5-b]pyridine
EINECS	Contact for details

Quality Control

Our 2-Chloromethyl-3-Methyl-3H-Imidazo[4,5-B]Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and structural identity. We provide Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our production adheres to cGMP principles where applicable, ensuring reliable quality and batch-to-batch consistency for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Recommended long-term storage temperature is 2-8°C (refrigerated). Allow the sealed container to reach room temperature before opening to minimize condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.