Description

1H-Pyrrolo[2,3-B]Pyridine, 5-Bromo-, 7-Oxide is a high-purity, advanced pharmaceutical intermediate and heterocyclic building block. This compound is critical for medicinal chemistry research and the synthesis of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce complex molecular scaffolds into their target molecules.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of kinase inhibitors and other biologically active molecules targeting various therapeutic areas.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies to explore novel chemical space.
• Agrochemical Synthesis: Serves as a precursor for developing new crop protection agents with unique modes of action.
• Fine Chemical Manufacturing: Employed in the multi-step synthesis of complex, high-value specialty chemicals.
• Academic & Contract Research: Essential for universities and CROs (Contract Research Organizations) conducting fundamental research in heterocyclic chemistry.
• Process Chemistry Development: Used to scale up and optimize synthetic routes for commercial production of target compounds.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine, 5-Bromo-, 7-Oxide
CAS No.	1092580-91-0
Molecular Formula	C7H5BrN2O
Molecular Weight	213.03 g/mol
Synonyms	5-Bromo-1H-pyrrolo[2,3-b]pyridine 7-oxide; 5-Bromo-7-azaindole N-oxide; 5-Bromo-1H-pyrrolo[2,3-b]pyridine N-oxide; 5-Bromo-7-azaindole 7-oxide; 5-Bromo-1H-7-azaindole N-oxide; 5-Bromo-7-aza-1H-indole 7-oxide; 5-Bromo-1H-pyrrolo[2,3-b]pyridine 1-oxide (tautomer); 5-Bromo-7-azaindole 1-oxide
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine, 5-Bromo-, 7-Oxide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.