Description

2-Piperazinone, 4-[5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-2-Pyridinyl]- is a high-value, heterocyclic boronic ester derivative that serves as a critical building block in modern synthetic chemistry. Its core value lies in enabling the efficient construction of complex molecular architectures through versatile cross-coupling reactions. This advanced intermediate is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other heterocyclic-based therapeutics.
• Suzuki-Miyaura Cross-Coupling Reagent: The pinacol boronate ester group makes it an essential reagent for forming carbon-carbon bonds under mild conditions, crucial for constructing complex organic molecules.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the piperazinone-pyridine scaffold can impart specific biological activity.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the creation of advanced polymers and organic electronic materials.
• Chemical Biology Probe Synthesis: Employed to create labeled compounds and molecular probes for studying biological pathways and target engagement.
• Process Chemistry & Scale-Up: Used in route development and optimization for the commercial-scale production of fine chemicals and active pharmaceutical ingredients (APIs).

Basic Information

Product Name	2-Piperazinone, 4-[5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-2-Pyridinyl]-
CAS No.	1092564-28-7
Molecular Formula	C15H22BN3O3
Molecular Weight	303.17 g/mol
Synonyms	4-(5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)piperazin-2-one; 4-(5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinyl)-2-piperazinone; 2-Piperazinone, 4-[5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinyl]-; 4-(5-(Pinacolatoboryl)pyridin-2-yl)piperazin-2-one; CAS 1092564-28-7; Boronic acid, B-[6-(2-oxo-1-piperazinyl)-3-pyridinyl]-, pinacol ester
EINECS	Contact for details

Quality Control

Our 2-Piperazinone, 4-[5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-2-Pyridinyl]- is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can support development activities requiring material for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C for optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.