Description

1-tert-Butyl 3-Methyl 5-Oxopyrrolidine-1,3-Dicarboxylate is a high-purity, protected pyrrolidinone derivative serving as a critical synthetic intermediate. This compound matters for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). Pharmaceutical R&D chemists and fine chemical manufacturers need it for advanced organic synthesis, including the preparation of proline analogs and other nitrogen-containing heterocycles essential for drug discovery programs.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of proline-based drug candidates and other pharmacologically active pyrrolidine derivatives.
• Peptidomimetics Research: Used in the design and synthesis of peptide mimics where the constrained pyrrolidinone ring influences conformation and biological activity.
• Agrochemical Synthesis: Intermediate in the production of advanced crop protection agents containing nitrogen heterocycles.
• Organocatalyst Development: Serves as a precursor for novel chiral catalysts and ligands used in asymmetric synthesis.
• Academic & Industrial R&D: Employed in methodological studies and scale-up processes for new synthetic routes to heterocyclic compounds.
• Custom Synthesis: Starting material for the contract manufacturing of specialized, high-value fine chemicals for various industries.

Basic Information

Product Name	1-tert-Butyl 3-Methyl 5-Oxopyrrolidine-1,3-Dicarboxylate
CAS No.	1092492-27-7
Molecular Formula	C12H19NO5
Molecular Weight	257.28 g/mol
Synonyms	1-tert-Butyl 3-methyl 5-oxo-1,3-pyrrolidinedicarboxylate; 5-Oxopyrrolidine-1,3-dicarboxylic acid 1-tert-butyl 3-methyl ester; 1-(tert-Butoxycarbonyl)-3-(methoxycarbonyl)-2-pyrrolidinone; tert-Butyl 3-(methoxycarbonyl)-5-oxo-1-pyrrolidinecarboxylate; 1-Boc-3-(methyloxycarbonyl)-2-pyrrolidinone; 1-Boc-3-methyl 5-oxopyrrolidine-1,3-dicarboxylate; N-Boc-3-methoxycarbonyl-2-pyrrolidinone
EINECS	Contact for details

Quality Control

Our 1-tert-Butyl 3-Methyl 5-Oxopyrrolidine-1,3-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles for pharmaceutical intermediates, ensuring traceability and consistency for critical R&D and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.