Description

3-(Trifluoromethyl)-1H-Pyrazolo[3,4-C]Pyridine is a high-value, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core structure, featuring a fused pyrazolo-pyridine ring system substituted with a trifluoromethyl group, makes it a critical intermediate for developing novel compounds with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating new active ingredients. Its unique scaffold is instrumental in modulating the pharmacokinetic and physicochemical profiles of candidate molecules.

Application

• Pharmaceutical Intermediate: Serves as a privileged scaffold in medicinal chemistry for the discovery and development of new drug candidates, particularly in oncology, CNS disorders, and anti-infective research.
• Agrochemical Research: Used as a key building block for synthesizing novel herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the trifluoromethyl group.
• Material Science Precursor: Acts as a starting material for synthesizing specialized ligands, organic semiconductors, or fluorinated polymers with unique electronic properties.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes and tool compounds for studying biological targets and pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke synthesis projects requiring complex fluorinated heterocycles.

Basic Information

Item	Details
Product Name	3-(Trifluoromethyl)-1H-Pyrazolo[3,4-C]Pyridine
CAS No.	1092459-55-6
Molecular Formula	C7H4F3N3
Molecular Weight	187.12 g/mol
Synonyms	3-(Trifluoromethyl)-1H-pyrazolo[3,4-c]pyridine; 1H-Pyrazolo[3,4-c]pyridine, 3-(trifluoromethyl)-; 3-Trifluoromethyl-1H-pyrazolo[3,4-c]pyridine; 3-(Trifluoromethyl)pyrazolo[3,4-c]pyridine; 1092459-55-6; 3-CF3-1H-pyrazolo[3,4-c]pyridine; 3-Trifluoromethyl-1H-7-azaindazole; Trifluoromethylpyrazolopyridine
EINECS	Contact for details

Quality Control

Every batch of 3-(Trifluoromethyl)-1H-Pyrazolo[3,4-C]Pyridine is manufactured under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment. Our quality protocols are designed to support applications in regulated environments, ensuring traceability, consistency, and reliability for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, containers should be kept tightly sealed under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.