Description

Methyl 3-Amino-5-Bromo-6-(2-Pyridinyl)Thieno[2,3-B]Pyridine-2-Carboxylate is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel, biologically active molecules, particularly in medicinal chemistry. It is primarily required by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, including kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of targeted drug candidates, especially within oncology and anti-inflammatory research pipelines.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the exploration of new chemical entities (NCEs).
• Kinase Inhibitor Development: Used in the construction of complex molecules designed to modulate specific kinase pathways involved in disease progression.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.
• Process Chemistry & Scale-Up: Employed in the optimization and pilot-scale production of active pharmaceutical ingredients (APIs).

Basic Information

Item	Details
Product Name	Methyl 3-Amino-5-Bromo-6-(2-Pyridinyl)Thieno[2,3-B]Pyridine-2-Carboxylate
CAS No.	1092352-72-1
Molecular Formula	C15H10BrN3O2S
Molecular Weight	376.23 g/mol
Synonyms	Methyl 3-amino-5-bromo-6-(pyridin-2-yl)thieno[2,3-b]pyridine-2-carboxylate; 1092352-72-1; Thieno[2,3-b]pyridine-2-carboxylic acid, 3-amino-5-bromo-6-(2-pyridinyl)-, methyl ester; 3-Amino-5-bromo-6-(2-pyridinyl)thieno[2,3-b]pyridine-2-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Every batch of Methyl 3-Amino-5-Bromo-6-(2-Pyridinyl)Thieno[2,3-B]Pyridine-2-Carboxylate is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality system is designed to meet the stringent requirements of pharmaceutical R&D and pre-clinical development. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC), identity confirmation (by IR, NMR, and/or MS), and impurity profile is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain long-term stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.