Description

Methyl 2,4-Dimethyl-3-Oxo-3,4-Dihydro-2H-1,4-Benzoxazine-7-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its benzoxazine core structure. This compound is of significant commercial importance for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic frameworks. It is primarily sought after by research institutions, custom synthesis organizations, and pharmaceutical manufacturers engaged in the development of new chemical entities and proprietary drug candidates.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of complex drug molecules, especially those targeting central nervous system (CNS) disorders, inflammation, or infectious diseases.
• Agrochemical Research: Used in the research and development of new herbicides, fungicides, or insecticides, leveraging its heterocyclic structure for bioactivity.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing novel benzoxazine-based libraries for high-throughput screening and structure-activity relationship (SAR) studies.
• Material Science Precursor: Potential use in the synthesis of specialty polymers, dyes, or photoactive materials due to its conjugated system and functional groups.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and cGMP production of client-specific target molecules.

Basic Information

Product Name	Methyl 2,4-Dimethyl-3-Oxo-3,4-Dihydro-2H-1,4-Benzoxazine-7-Carboxylate
CAS No.	1092352-44-7
Molecular Formula	C13H15NO4
Molecular Weight	249.26 g/mol
Synonyms	Methyl 2,4-dimethyl-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazine-7-carboxylate; 7-Carbonmethoxy-2,4-dimethyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazine; 2,4-Dimethyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-7-carboxylic acid methyl ester; 1,4-Benzoxazine-7-carboxylic acid, 3,4-dihydro-2,4-dimethyl-3-oxo-, methyl ester; CAS 1092352-44-7
EINECS	Contact for details

Quality Control

Our production of Methyl 2,4-Dimethyl-3-Oxo-3,4-Dihydro-2H-1,4-Benzoxazine-7-Carboxylate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and tested against rigorous in-house specifications, which typically include identity confirmation (IR, NMR), purity assay (HPLC), and control of related substances. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment. We support customer audits and can tailor specifications to meet specific project requirements, including those for cGMP intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any individual impurity ≤ 0.5% Total impurities ≤ 1.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.